Aslam et al., 2013
A multi-mineral-rich natural product from red marine algae preserves bone structure and function in C57BL/6 Mice
MN Aslam, M Naik, I Bergin, K Jepsen, JM Kreider, KH Graf, SA Goldstein & J Varani
Depts of Pathology & Orthopaedic Surgery, University of Michigan, USA
Biol Trace Elem Res 2013
This study investigated the effects of Aquamin on bone structure and function. As one of the risk factors for bone health is a high fat western-style diet (HFWD), a mouse version of a HFWD was prepared. This diet is high in saturated fat and carbohydrates and low in fibre, calcium & Vit D.
Study Details:
280 mice were maintained for up to 18 months either on a HFWD diet or on a low-fat normal mouse diet with or without Aquamin supplementation.
Results:
•Female mice rapidly lost bone (femoral and vertebral) on both diets. Bone loss also occurred in male mice but not as rapidly or to the same extent as females.
•Aquamin reduced the loss of both trabecular and cortical bone and preserved bone strength.
•Long bones were pooled and assessed at each time point for levels of the minerals present in Aquamin.
•The most striking result was a 5-10 fold increase in strontium levels in bone in the presence of Aquamin.
•There was an increase in levels of calcium, magnesium and potassium in the presence of Aquamin. The levels of iron, zinc & manganese were excessively high in the HFWD and reduced to normal range in the presence of Aquamin. Boron, copper and selenium levels were below detectable levels.
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